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nicorandil

NICORANDIL

  • It belongs to a novel class of agents of the management of coronary heart diseases.
  • It has a dual mode of acton being a selective ATP dependent  potassium channel opener and a nitric oxide donor.
INDICATONS :
  • Long term management of coronary heart disease
DOSE :
  • ADULTS : 10-20 mg twice day
  • CHILDREN : Not recommended.
CONTRAINDICATIONS :
  • Hypersensitivity
  • Patients with cardiogenic shock
  • left ventricular failure with low filling pressure and in hypotension.
SPECIAL PRECAUTIONS :
  • Patients on Nicorandil theraypy should not drive or operate machinery.
      IT AVOIDED IN THE PATIENTS WITH
  • depleted blood volume
  • low systolic blood pressure
  • acute pulmonary oedema or Acutue Myocardial infarctions
  • Acute left ventricular failure and low filling pressure.
  • Paediatric : Not recommended.
  • Pregnancy and Lactaion :Should not be used as there is no experience in humans.
  • Elderly : No special problem.
SIDE EFFECTS :
  • Headache.
  • Cutaneous vasodilation with flushing.
  • Nausea.
  • Vomiting.
  • Dizziness.
  • Feeling of weakness.
DRUG INTERACTIONS :
                     No pharmacological or pharmacokinetic interactons have been observed with
  • Beta-blockers
  • Digoxin
  • Rifampicin
  • Cimetidine
  • Frusemide
 I inviting the people who intrest to publish your mateirals in the website

Contact :
Email : krs986@gmail.com
Cell : 9059999716

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